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Skiing the black diamond slope: progress on the biochemistry of translesion DNA synthesis.挑战高难度滑雪道：跨损伤DNA合成的生物化学进展
Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10348-50. doi: 10.1073/pnas.95.18.10348.
2
SOS factors involved in translesion synthesis.参与跨损伤合成的SOS因子。
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The beta subunit modulates bypass and termination at UV lesions during in vitro replication with DNA polymerase III holoenzyme of Escherichia coli.在使用大肠杆菌DNA聚合酶III全酶进行体外复制期间，β亚基调节紫外线损伤处的旁路和终止。
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Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III.纯化的诱变蛋白UmuC、UmuD'和RecA在DNA聚合酶III对无碱基DNA损伤进行复制性跨越过程中的活性。
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[DNA polymerase zeta (zeta) and error-prone translesion replication].[DNA聚合酶ζ（ζ）与易出错的跨损伤复制]
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A phenotype for enigmatic DNA polymerase II: a pivotal role for pol II in replication restart in UV-irradiated Escherichia coli.神秘的DNA聚合酶II的一种表型：在紫外线照射的大肠杆菌中，聚合酶II在复制重新启动中起关键作用。
Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9224-9. doi: 10.1073/pnas.96.16.9224.

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The discovery of error-prone DNA polymerase V and its unique regulation by RecA and ATP.易错DNA聚合酶V的发现及其受RecA和ATP的独特调控。
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Genetic interactions between the Escherichia coli umuDC gene products and the beta processivity clamp of the replicative DNA polymerase.大肠杆菌umuDC基因产物与复制性DNA聚合酶的β持续性钳之间的遗传相互作用。
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A role for the umuDC gene products of Escherichia coli in increasing resistance to DNA damage in stationary phase by inhibiting the transition to exponential growth.大肠杆菌的umuDC基因产物通过抑制向指数生长的转变在增强对数期对DNA损伤的抗性中所起的作用。
J Bacteriol. 2000 Feb;182(4):1127-35. doi: 10.1128/JB.182.4.1127-1135.2000.
9
The Escherichia coli SOS mutagenesis proteins UmuD and UmuD' interact physically with the replicative DNA polymerase.大肠杆菌SOS诱变蛋白UmuD和UmuD' 与复制性DNA聚合酶发生物理相互作用。
Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12373-8. doi: 10.1073/pnas.96.22.12373.
10
Mutations affecting the ability of the Escherichia coli UmuD' protein to participate in SOS mutagenesis.影响大肠杆菌UmuD'蛋白参与SOS诱变能力的突变。
J Bacteriol. 1999 Jan;181(1):177-85. doi: 10.1128/JB.181.1.177-185.1999.

本文引用的文献

1
The mutagenesis proteins UmuD' and UmuC prevent lethal frameshifts while increasing base substitution mutations.诱变蛋白UmuD'和UmuC可防止致死性移码，同时增加碱基置换突变。
Mol Cell. 1998 Aug;2(2):191-9. doi: 10.1016/s1097-2765(00)80129-x.
2
Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein.大肠杆菌中SOS诱导突变的生化基础：依赖UmuD'2C诱变复合物和RecA蛋白的体外损伤旁路重建。
Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9755-60. doi: 10.1073/pnas.95.17.9755.
3
A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta.酿酒酵母REV3基因的人类同源基因，该基因编码DNA聚合酶ζ的催化亚基。
Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6876-80. doi: 10.1073/pnas.95.12.6876.
4
Polymerases and the replisome: machines within machines.聚合酶与复制体：机器中的机器
Cell. 1998 Feb 6;92(3):295-305. doi: 10.1016/s0092-8674(00)80923-x.
5
The cell as a collection of protein machines: preparing the next generation of molecular biologists.作为蛋白质机器集合的细胞：培养下一代分子生物学家。
Cell. 1998 Feb 6;92(3):291-4. doi: 10.1016/s0092-8674(00)80922-8.
6
Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis.溶液中UmuD'蛋白的二聚化及其对SOS诱变调控的影响。
Nat Struct Biol. 1997 Dec;4(12):979-83. doi: 10.1038/nsb1297-979.
7
Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach.采用单半胱氨酸方法对完整的UmuD中氨基酸30至42之间的区域进行分析。
J Bacteriol. 1996 Dec;178(24):7295-303. doi: 10.1128/jb.178.24.7295-7303.1996.
8
Interactions of Escherichia coli UmuD with activated RecA analyzed by cross-linking UmuD monocysteine derivatives.通过交联UmuD单半胱氨酸衍生物分析大肠杆菌UmuD与活化RecA的相互作用。
J Bacteriol. 1996 Dec;178(24):7285-94. doi: 10.1128/jb.178.24.7285-7294.1996.
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Deoxycytidyl transferase activity of yeast REV1 protein.酵母REV1蛋白的脱氧胞苷转移酶活性。
Nature. 1996 Aug 22;382(6593):729-31. doi: 10.1038/382729a0.
10
Thymine-thymine dimer bypass by yeast DNA polymerase zeta.酵母DNA聚合酶ζ对胸腺嘧啶-胸腺嘧啶二聚体的绕过
Science. 1996 Jun 14;272(5268):1646-9. doi: 10.1126/science.272.5268.1646.

Skiing the black diamond slope: progress on the biochemistry of translesion DNA synthesis.

作者信息

Walker G C

机构信息

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

出版信息

Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10348-50. doi: 10.1073/pnas.95.18.10348.

DOI:10.1073/pnas.95.18.10348
PMID:9724704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC33885/
Abstract
摘要