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在接受茚地那韦治疗的HIV患者中,非不透光晶体沉积导致输尿管梗阻。

Nonopaque crystal deposition causing ureteric obstruction in patients with HIV undergoing indinavir therapy.

作者信息

Blake S P, McNicholas M M, Raptopoulos V

机构信息

Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

出版信息

AJR Am J Roentgenol. 1998 Sep;171(3):717-20. doi: 10.2214/ajr.171.3.9725303.

DOI:10.2214/ajr.171.3.9725303
PMID:9725303
Abstract

OBJECTIVE

We describe the unique CT features of ureteric calculi in six HIV-infected patients receiving indinavir, the most commonly used HIV protease inhibitor, which is associated with an increased incidence of urolithiasis.

CONCLUSION

Ureteric obstruction caused by precipitated indinavir crystals may be difficult to diagnose with unenhanced CT. The calculi are not opaque, and secondary signs of obstruction may be absent or minimal and should be sought carefully. Images may need to be obtained using i.v. contrast material to enable diagnosis of ureteric stones or obstruction in patients with HIV infection who receive indinavir therapy.

摘要

目的

我们描述了6例接受茚地那韦治疗的HIV感染患者输尿管结石的独特CT特征。茚地那韦是最常用的HIV蛋白酶抑制剂,与尿路结石发病率增加有关。

结论

由茚地那韦结晶沉淀引起的输尿管梗阻可能难以通过平扫CT诊断。结石并非不透光,梗阻的继发征象可能不存在或很轻微,应仔细寻找。可能需要使用静脉造影剂来获取图像,以便对接受茚地那韦治疗的HIV感染患者的输尿管结石或梗阻进行诊断。

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Nonopaque crystal deposition causing ureteric obstruction in patients with HIV undergoing indinavir therapy.在接受茚地那韦治疗的HIV患者中,非不透光晶体沉积导致输尿管梗阻。
AJR Am J Roentgenol. 1998 Sep;171(3):717-20. doi: 10.2214/ajr.171.3.9725303.
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Indinavir urinary stones as origin of upper urinary tract obstruction.茚地那韦尿路结石作为上尿路梗阻的病因
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