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肝细胞癌的细针穿刺细胞学检查

Fine needle aspiration cytology of hepatocellular carcinoma.

作者信息

Devi V L, Hazarika D

机构信息

Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore.

出版信息

Indian J Pathol Microbiol. 1995 Oct;38(4):389-92.

PMID:9726149
Abstract

Fine needle aspiration cytology (FNAC) is an extremely useful technique in the evaluation of hepatic masses. This study was undertaken with the aim of describing the morphological spectrum seen in fine needle aspirates from hepatocellular carcinoma (HCC) seen in our patients hailing from South India. Thirty two cases of HCC were studied. Trabacular pattern covered by endothelium was the most common. Pseudoglandular, spindle cell and dispersed patterns were also seen. Individual tumour cells were generally reminiscent of hepatocytes, and had a prominent nucleolus. The presence of intranuclear and intracytoplasmic inclusions were notable features. FNA cytology in HCC is sufficiently distinctive to form an invaluable tool in the diagnosis of this malignancy.

摘要

细针穿刺细胞学检查(FNAC)是评估肝脏肿块的一项极其有用的技术。本研究旨在描述来自印度南部的患者肝细胞癌(HCC)细针穿刺物中所见的形态学谱。对32例HCC病例进行了研究。最常见的是被内皮覆盖的小梁状模式。也可见假腺管、梭形细胞和散在模式。单个肿瘤细胞通常使人联想到肝细胞,并有一个明显的核仁。核内和胞质内包涵体的存在是显著特征。HCC中的FNA细胞学具有足够的特异性,可成为诊断这种恶性肿瘤的一项宝贵工具。

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