纤维板层型肝细胞癌的细针穿刺抽吸细胞学检查
Fine needle aspiration cytology of fibrolamellar hepatocellular carcinoma.
作者信息
Suen K C, Magee J F, Halparin L S, Chan N H, Greene C A
出版信息
Acta Cytol. 1985 Sep-Oct;29(5):867-72.
The major cytologic features seen in fine needle aspirates from two cases of fibrolamellar hepatocellular carcinoma were: liver-like tumor cells, characterized by plump, polygonal forms with eosinophilic, granular cytoplasm; large oval nuclei with extremely prominent solitary nucleoli; and parallel bands of fibrous tissue and fibrocytes seen within the tumor fragments. Other helpful features included intracytoplasmic hyaline globules and well-delineated pale bodies. Clinically, the tumors occurred in young patients with noncirrhotic livers and ran a more favorable course than do other types of hepatocellular carcinoma.
两例纤维板层型肝细胞癌细针穿刺抽吸物中所见的主要细胞学特征为
肝样肿瘤细胞，其特征为细胞丰满、呈多边形，胞质嗜酸性、颗粒状；大的椭圆形细胞核，核仁极其突出且单个存在；肿瘤碎片内可见平行的纤维组织带和成纤维细胞。其他有用的特征包括胞质内透明小球和界限清楚的淡染小体。临床上，这些肿瘤发生于无肝硬化的年轻患者，与其他类型的肝细胞癌相比，病程更为良好。
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