用3,4-苯并芘诱导NMRI小鼠卵母细胞和中国仓鼠骨髓细胞的染色体畸变。
Chromosome aberrations in oocytes of NMRI mice and bone marrow cells of Chinese hamsters induced with 3,4-benzpyrene.
作者信息
Basler A, Röhrborn G
出版信息
Mutat Res. 1976 Oct;38(5):327-32. doi: 10.1016/0165-1161(76)90157-6.
PMID:972619
Abstract
This paper deals with mutagenicity tests with 3,4-benzpyrene in mice oocytes of the strain NMRI and Chinese hamster bone-marrow cells. The mutagenic effect of this hydrocarbon was observed in both test systems. Investigations of bone-marrow chromosomes clearly show dose-response curves.
摘要
本文研究了3,4-苯并芘对NMRI品系小鼠卵母细胞和中国仓鼠骨髓细胞的致突变性试验。在这两种试验系统中均观察到了这种碳氢化合物的诱变作用。对骨髓染色体的研究清楚地显示出剂量反应曲线。
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