World Health Organ Tech Rep Ser. 1998;879:i-vi, 1-73.
This report presents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in foods and to recommend maximum levels for such residues in food. The first part of the report considers standards for the performance of studies, residues at the injection site, and several initiatives to promote transparency of the process for setting Maximum Residue Limits (MRLs). A summary follows of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: two anthelminthic agents (moxidectin and tiabendazole), eight antimicrobial agents (ceftiofur, danofloxacin, dihydrostreptomycin, streptomycin, enrofloxacin, flumequine, gentamicin and spiramycin), one glucocorticosteroid (dexamethasone), and two insecticides (cyfluthrin and fluazuron). Annexed to the report are a summary of the Committee's recommendations on these drugs, including Acceptable Daily Intakes and MRL's and further toxicological studies and other information required.
本报告介绍了粮农组织/世卫组织联合专家委员会的结论,该委员会召开会议旨在评估某些兽药在食品中的残留安全性,并就食品中此类残留的最高限量提出建议。报告的第一部分审议了研究开展的标准、注射部位的残留以及多项旨在提高设定最大残留限量(MRLs)过程透明度的举措。以下是委员会对多种兽药的毒理学和残留数据的评估总结:两种驱虫剂(莫西菌素和噻苯达唑)、八种抗菌剂(头孢噻呋、达氟沙星、二氢链霉素、链霉素、恩诺沙星、氟甲喹、庆大霉素和螺旋霉素)、一种糖皮质激素(地塞米松)以及两种杀虫剂(氟氯氰菊酯和氟虫脲)。报告附录中有委员会关于这些药物的建议总结,包括每日允许摄入量和最大残留限量,以及所需的进一步毒理学研究和其他信息。