华氏巨球蛋白血症中的上睑下垂
Ptosis in Waldenström's macroglobulinemia.
作者信息
Klapper S R, Jordan D R, Pelletier C, Brownstein S, Punja K
机构信息
University of Ottawa Eye Institute, Ontario, Canada.
出版信息
Am J Ophthalmol. 1998 Aug;126(2):315-7. doi: 10.1016/s0002-9394(98)00166-4.
PURPOSE
To report a case of chronic, progressive unilateral blepharoptosis in a 73-year-old woman with Waldenström's macroglobulinemia.
METHOD
Case report. A biopsy was performed on a thickened and indurated tarsal plate that we believed had resulted in mechanical blepharoptosis.
RESULTS
Histologic and immunohistochemistry studies of the biopsy specimen demonstrated a lymphoplasmacytoid cell infiltrate with monoclonal antibodies consistent with Waldenström's macroglobulinemia.
CONCLUSION
Involvement of the tarsal conjunctiva and tarsus in Waldenstrom's macroglobulinemia is a newly recognized cause of eyelid thickening and ptosis.
目的
报告一例73岁患有华氏巨球蛋白血症的女性慢性进行性单侧上睑下垂病例。
方法
病例报告。对增厚变硬的睑板进行活检，我们认为这导致了机械性上睑下垂。
结果
活检标本的组织学和免疫组化研究显示淋巴细胞浆细胞样细胞浸润，单克隆抗体检测结果与华氏巨球蛋白血症一致。
结论
华氏巨球蛋白血症累及睑结膜和睑板是眼睑增厚和上睑下垂新发现的病因。
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