Varga J, Fodor L
Department of Microbiology and Infectious Diseases, University of Veterinary Science, Budapest, Hungary.
Zentralbl Bakteriol. 1998 Jul;288(1):67-73. doi: 10.1016/s0934-8840(98)80101-1.
During August and September 1995, 111 thermopilic campylobacters from stool samples of patients suffering from diarrhoea were cultured and f1amined. Biochemical characteristics, serological distribution and antibiotic susceptibility of the strains were examined and the age distribution of the patients affected was recorded. Most of the strains, i.e. 101 isolates (91%) proved to be Campylobacter (C.) jejuni, whereas 10 strains (9%) were C. coli. On the basis of their heat-stable antigens, 66 strains (65.3%) of C. jejuni could be assigned to 17 serogroups, of which serogroups 2 (15 strains, 14.8%) and 8 (10 strains, 9.9%) occurred most frequently. All isolates examined were susceptible to erythromycin whereas susceptibility to other antibiotics varied greatly. Children under five years of age (59 cases = 53.1%) were most frequently affected. During 1995, altogether 11,976 human Campylobacter cases were recorded in Hungary which means a prevalence of 114/100,000. The results suggest that the great majority of cases of Campylobacter diarrhoea is caused by C. jejuni strains while C. coli strains have much less significance. The serotype distribution of C. jejuni strains causing diarrhoea is very wide. If treatment is needed the best choice at present seems to be erythromycin.
1995年8月至9月期间，从腹泻患者的粪便样本中培养并鉴定了111株嗜热弯曲菌。对这些菌株的生化特性、血清学分布和抗生素敏感性进行了检测，并记录了受影响患者的年龄分布。大多数菌株，即101株分离株（91%）被证明为空肠弯曲菌，而10株（9%）为大肠弯曲菌。根据其热稳定抗原，66株（65.3%）空肠弯曲菌可归为17个血清群，其中血清群2（15株，14.8%）和血清群8（10株，9.9%）最为常见。所有检测的分离株对红霉素敏感，而对其他抗生素的敏感性差异很大。五岁以下儿童受影响最为频繁（59例=53.1%）。1995年，匈牙利共记录了11976例人类弯曲菌病例，这意味着患病率为114/10万。结果表明，绝大多数弯曲菌腹泻病例是由空肠弯曲菌菌株引起的，而大肠弯曲菌菌株的重要性要小得多。引起腹泻的空肠弯曲菌菌株的血清型分布非常广泛。如果需要治疗，目前最佳选择似乎是红霉素。
