[厄瓜多尔洛哈市腹泻儿童中弯曲杆菌和空肠弯曲杆菌的流行情况及抗菌行为]
[Prevalence and antimicrobial behavior of Campylobacter jejuni and Campylobacter coli in children with diarrhea in Loja city, Ecuador].
作者信息
Simaluiza Rosa, Toledo Zorayda, Fernández Heriberto
机构信息
Sección Genética Humana, Microbiología y Bioquímica Clínica, Departamento de Ciencias de la Salud, Universidad Técnica Particular de Loja, Loja, Ecuador.
Instituto de Microbiología Clínica, Universidad Austral de Chile, Valdivia, Chile.
出版信息
Rev Chilena Infectol. 2018 Apr;35(2):213-215. doi: 10.4067/s0716-10182018000200213.
INTRODUCTION
Campylobacter is an important agent of diarrhea in humans. In Ecuador, the information on Campylobacter is scarce and there are not antecedents about antimicrobial susceptibility.
OBJECTIVE
To describe Campylobacter prevalence in children with diarrhea and their behavior against five antimicrobials in vitro.
METHOD
We studied 253 children with diarrhea aging 7 months to 9 years who consulted for diarrhea in two hospitals in the city of Loja. Fecal samples were cultured and identification by tests by phenotypic tests and multiplex PCR. Susceptibility to 5 antibiotics was determined by the disc-diffusion method.
RESULTS
Campylobacter was found in 16 (6.3%) children, being C. jejuni the most frequent one (5.1%), followed by C. coli (1.2%). All strains were susceptible to gentamicin and ampicillin/clavulanic acid, being found low resistance to ampicillin and erythromycin and high resistance to ciprofloxacin.
引言
弯曲杆菌是人类腹泻的重要病原体。在厄瓜多尔，关于弯曲杆菌的信息匮乏，且尚无抗菌药物敏感性的相关记录。
目的
描述腹泻儿童中弯曲杆菌的流行情况及其对五种抗菌药物的体外药敏表现。
方法
我们研究了253名年龄在7个月至9岁之间因腹泻到洛哈市两家医院就诊的腹泻儿童。粪便样本经培养后通过表型试验和多重PCR进行鉴定。采用纸片扩散法测定对5种抗生素的敏感性。
结果
在16名（6.3%）儿童中发现了弯曲杆菌，其中空肠弯曲杆菌最为常见（5.1%），其次是大肠弯曲杆菌（1.2%）。所有菌株对庆大霉素和氨苄西林/克拉维酸敏感，对氨苄西林和红霉素有低水平耐药，对环丙沙星有高水平耐药。
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