冠状动脉搭桥术前的孤独感可能是术后短期和长期死亡率的一个预测指标。

The feeling of loneliness prior to coronary artery bypass grafting might be a predictor of short-and long-term postoperative mortality.

作者信息

Herlitz J, Wiklund I, Caidahl K, Hartford M, Haglid M, Karlsson B W, Sjöland H, Karlsson T

机构信息

Division of Cardiology, Sahlgrenska University Hospital, Göteborg, Sweden.

出版信息

Eur J Vasc Endovasc Surg. 1998 Aug;16(2):120-5. doi: 10.1016/s1078-5884(98)80152-4.

DOI:10.1016/s1078-5884(98)80152-4

PMID:9728430

Abstract

OBJECTIVES

To evaluate the effect of different aspects of quality of life (QL) upon mortality during short-and long-term follow-up after coronary artery bypass grafting (CABG).

DESIGN

Prospective evaluation.

MATERIALS

Consecutive patients from western Sweden who during 3 years underwent CABG.

METHODS

They answered a questionnaire at the time of coronary angiography prior to CABG. Quality of life was measured with questions from the Nottingham Health Profile (NHP) part I.

RESULTS

In all, 1290 patients were included in the analyses. When accounting for various preoperative factors known to be independently associated with morality the NHP question "I feel lonely" was found to be associated with mortality, both at 30 days (RR 2.61; 95% CI 1.15-5.95; p = 0.02) and at 5 years (RR 1.78; 95% CI 1.17-2.71; p = 0.007) after the operation. Thirteen per cent reported they felt lonely. At 5 years was, in addition, the statement "I have difficulty climbing stairs" also independently associated with mortality (RR 1.50; 95% CI 1.02-2.22; p = 0.04).

CONCLUSION

Among the 38 statements in NHP as a judgment of QL prior to CABG, one of them, "I feel lonely" was independently associated with survival both at 30 days and 5 years after CABG.

摘要

目的

评估冠状动脉旁路移植术（CABG）后短期和长期随访期间生活质量（QL）的不同方面对死亡率的影响。

设计

前瞻性评估。

材料

来自瑞典西部的连续患者，他们在3年期间接受了CABG。

方法

他们在CABG术前冠状动脉造影时回答了一份问卷。使用诺丁汉健康量表（NHP）第一部分的问题来测量生活质量。

结果

总共1290名患者纳入分析。在考虑各种已知与死亡率独立相关的术前因素后，发现NHP问题“我感到孤独”与术后30天（相对危险度[RR] 2.61；95%置信区间[CI] 1.15 - 5.95；p = 0.02）和5年（RR 1.78；95% CI 1.17 - 2.71；p = 0.007）的死亡率相关。13%的患者报告他们感到孤独。此外，在5年时，“我爬楼梯有困难”这一表述也与死亡率独立相关（RR 1.50；95% CI 1.02 - 2.22；p = 0.04）。