Vobecký M, Babický A, Lener J, Pavelka S
Institute of Analytical Chemistry, Academy of Sciences of the Czech Republic, Prague.
Physiol Res. 1997;46(5):385-9.
The biological half-life of bromine in the rat thyroid was determined by measuring the radioactivity of thyroids of animals which continuously received 82Br labelled bromide in their food. The value of this half-life (110 h) is practically the same as the biological half-life of iodine. The rate of establishing the I/Br concentration ratio in the thyroid depends on the biological half-life of bromine. The mechanism of this process depends on the state of iodine supply. When the supply is sufficient, the iodine concentration in the thyroid remains constant, while during iodine deficiency the iodine atoms are replaced by atoms of bromine.
通过测量持续在食物中摄入82Br标记溴化物的动物甲状腺的放射性，确定了溴在大鼠甲状腺中的生物半衰期。该半衰期值（110小时）实际上与碘的生物半衰期相同。甲状腺中碘/溴浓度比的建立速率取决于溴的生物半衰期。这个过程的机制取决于碘的供应状态。当供应充足时，甲状腺中的碘浓度保持恒定，而在碘缺乏期间，碘原子被溴原子取代。
