Kühlbrandt W, Auer M, Scarborough G A
Max-Planck-Institut für Biophysik, Abteilung Strukturbiologie, Frankfurt am Main, Germany.
Curr Opin Struct Biol. 1998 Aug;8(4):510-6. doi: 10.1016/s0959-440x(98)80130-9.
Electron cryocrystallography of precipitant-induced two-dimensional surface crystals of the neurospora plasma membrane H+ - ATPase and tubular crystals of the sarcoplasmic reticulum Ca(2+)-ATPase has recently yielded structure maps for these ion transporters at a resolution of about 8 A. The membrane-embedded regions of these closely related enzymes are similar, but the cytoplasmic regions appear to be significantly different.
最近，利用电子低温晶体学技术对粗糙脉孢菌质膜H⁺-ATP酶沉淀剂诱导的二维表面晶体和肌质网Ca²⁺-ATP酶管状晶体进行研究，已获得这些离子转运蛋白分辨率约为8埃的结构图。这些密切相关的酶的膜嵌入区域相似，但胞质区域似乎有显著差异。
