An Y H, Friedman R J
Department of Orthopaedic Surgery, Medical University of South Carolina, Charleston, USA.
J Biomed Mater Res. 1998 Fall;43(3):338-48. doi: 10.1002/(sici)1097-4636(199823)43:3<338::aid-jbm16>3.0.co;2-b.
This article reviews the mechanisms of bacterial adhesion to biomaterial surfaces and the factors affecting the adhesion. The process of bacterial adhesion includes an initial physicochemical interaction phase (phase one) and a late molecular and cellular interaction phase (phase two), which is a complicated process affected by many factors, including the characteristics of the bacteria themselves, the target material surface, and the environmental factors, such as the presence of serum proteins or bactericidal substances.
本文综述了细菌粘附于生物材料表面的机制以及影响粘附的因素。细菌粘附过程包括初始物理化学相互作用阶段（第一阶段）和后期分子与细胞相互作用阶段（第二阶段），这是一个受多种因素影响的复杂过程，这些因素包括细菌自身特性、目标材料表面以及环境因素，如血清蛋白或杀菌物质的存在。
