Alabdulkareem A S, Abahussein A A, Okoro A
Department of Dermatology, King Fahd Hospital of the University, Dammam, Saudi Arabia.
Int J Dermatol. 1998 Aug;37(8):622-4. doi: 10.1046/j.1365-4362.1998.00422.x.
Treatment of severe alopecia areata is difficult, and most efforts to successfully treat this condition have been disappointing. Systemic corticosteroids have been demonstrated as an effective treatment of severe alopecia areata.
Eighteen patients with alopecia areata (extensive patchy and totalis universalis types) were treated with systemic corticosteroids.
Satisfactory hair regrowth was achieved in seven patients (38.9%). Hair fall subsequently occurred in all of these patients on discontinuation or tapering of corticosteroid therapy.
Systemic corticosteroid therapy does not prevent the spread or relapse of severe alopecia areata and, when complete regrowth is obtained, it is rarely maintained off therapy.
重度斑秃的治疗较为困难，大多数成功治疗该病症的努力都令人失望。全身用皮质类固醇已被证明是治疗重度斑秃的一种有效方法。
18例斑秃患者（广泛斑片状和全秃普秃型）接受了全身用皮质类固醇治疗。
7例患者（38.9%）实现了满意的毛发再生。在停用或逐渐减少皮质类固醇治疗后，所有这些患者随后都出现了脱发。
全身用皮质类固醇疗法不能预防重度斑秃的扩散或复发，而且当实现完全再生时，很少能在停药后维持。
