Sekine I, Kodama T, Yokose T, Nishiwaki Y, Suzuki K, Goto K, Nagai K, Kuriyama T
Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
Oncology. 1998 Sep-Oct;55(5):431-4. doi: 10.1159/000011891.
In a review of pulmonary tumors diagnosed at our institute from 1976 to 1995, we found 20 malignant and 12 benign rare tumors, which accounted for 0.57 and 0.34% of all pulmonary tumors, respectively. The histological types of these rare malignant tumors were malignant lymphoma (6/20), carcinosarcoma (3/20), mucoepidermoid carcinoma (2/20), bronchial gland mixed tumor (2/20), adenocystic carcinoma (1/20), myoepithelioma (1/20), leiomyosarcoma (1/20), epitheloid hemangioendothelioma (1/20), hemangiopericytoma (1/20), malignant melanoma (1/20) and choriocarcinoma (1/20). Benign rare tumors involved papilloma (3/12), lipoma (3/12), leiomyoma (3/12), adenoma (1/12), fibroma (1/12), and meningioma (1/12). The clinical and pathological features of malignant tumors were roughly the same as those of common pulmonary carcinomas. In contrast, benign tumors were never larger than 3 cm and were more commonly located in the central parts of the lung, which explained the relatively frequent symptoms of wheezing and fever associated with obstructive pneumonia.
在对我院1976年至1995年诊断的肺部肿瘤进行回顾时,我们发现了20例恶性罕见肿瘤和12例良性罕见肿瘤,分别占所有肺部肿瘤的0.57%和0.34%。这些罕见恶性肿瘤的组织学类型包括恶性淋巴瘤(6/20)、癌肉瘤(3/20)、黏液表皮样癌(2/20)、支气管腺混合瘤(2/20)、腺囊性癌(1/20)、肌上皮瘤(1/20)、平滑肌肉瘤(1/20)、上皮样血管内皮瘤(1/20)、血管外皮细胞瘤(1/20)、恶性黑色素瘤(1/20)和绒毛膜癌(1/20)。良性罕见肿瘤包括乳头状瘤(3/12)、脂肪瘤(3/12)、平滑肌瘤(3/12)、腺瘤(1/12)、纤维瘤(1/12)和脑膜瘤(1/12)。恶性肿瘤的临床和病理特征与常见肺癌大致相同。相比之下,良性肿瘤从不大于3厘米,且更常见于肺中央部位,这解释了与阻塞性肺炎相关的喘息和发热症状相对频繁的原因。