Ehirim P U, Kerr D S, Cohen A R
Division of Pediatric Neurosurgery, Rainbow Babies and Childrens Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Pediatr Neurosurg. 1998 Apr;28(4):195-7. doi: 10.1159/000028649.
Pituitary macroadenomas occur infrequently in children and can present with visual dysfunction or endocrinopathy. Occasionally, primary end-organ failure can cause reactive enlargement of the pituitary gland that may be clinically and radiographically indistinguishable from pituitary macroadenoma. The authors describe an example of reactive pituitary hyperplasia from primary hypothyroidism that mimicked a pituitary macroadenoma in a child. Recognition of this entity, which responds to medical therapy, is important because it can spare patients unnecessary surgery.
垂体大腺瘤在儿童中很少见，可表现为视觉功能障碍或内分泌病。偶尔，原发性终末器官功能衰竭可导致垂体反应性增大，在临床和影像学上可能与垂体大腺瘤无法区分。作者描述了一例原发性甲状腺功能减退引起的反应性垂体增生病例，该病例在一名儿童中酷似垂体大腺瘤。认识到这种对药物治疗有反应的实体很重要，因为它可以避免患者进行不必要的手术。
