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白来航鸡小肠中α-甲基-D-葡萄糖苷和L-脯氨酸摄取的发育研究

Developmental study of alpha-methyl-D-glucoside and L-proline uptake in the small intestine of the White Leghorn chicken.

作者信息

Soriano M E, Planas J M

机构信息

Department de Fisiologia-Divisió IV, Facultat de Farmàcia, Universitat de Barcelona, Spain.

出版信息

Poult Sci. 1998 Sep;77(9):1347-53. doi: 10.1093/ps/77.9.1347.

DOI:10.1093/ps/77.9.1347
PMID:9733122
Abstract

Development changes in alpha-methyl-D-glucoside and L-proline accumulation were studied using everted sleeves from the duodenum, jejunum, and ileum of chickens. Six age groups of chickens were used: 1 d and 1, 2, 3, 5 to 6, and 12 to 14 wk. Our results showed the presence of a Na+-dependent mechanism of sugar and amino acid uptake that is already fully developed at hatch. The intestinal transport activity undergoes substantial changes with age and region studied. Intracellular accumulation of alpha-methyl-D-glucoside and L-proline was greater in newly hatched chicks and then declined with age in the three regions of the small intestine, except for L-proline transport in ileum, which remained constant during the period studied. The transport mechanisms for each nutrient followed separate developmental patterns along the small intestine during the period studied.

摘要

利用鸡十二指肠、空肠和回肠的外翻肠段,研究了α-甲基-D-葡萄糖苷和L-脯氨酸积累的发育变化。使用了六个年龄组的鸡:1日龄以及1、2、3、5至6周龄和12至14周龄。我们的结果表明,糖和氨基酸摄取存在一种依赖钠离子的机制,这种机制在孵化时就已完全发育。肠道转运活性随所研究的年龄和区域而发生显著变化。新孵出雏鸡小肠三个区域中α-甲基-D-葡萄糖苷和L-脯氨酸的细胞内积累量较大,随后随年龄增长而下降,但回肠中L-脯氨酸的转运在所研究期间保持恒定。在所研究期间,每种营养物质的转运机制沿小肠遵循各自的发育模式。

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