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经颅多普勒超声检查评估脑积水患儿脑脊液引流的必要性。

Transcranial Doppler ultrasonography to evaluate need for cerebrospinal fluid drainage in hydrocephalic children.

作者信息

Westra S J, Lazareff J, Curran J G, Sayre J W, Kawamoto H

机构信息

Department of Radiological Sciences, UCLA School of Medicine, Los Angeles, California 90095-1721, USA.

出版信息

J Ultrasound Med. 1998 Sep;17(9):561-9. doi: 10.7863/jum.1998.17.9.561.

Abstract

The aim of this study was to determine whether the resistive index in the anterior cerebral artery, as measured by transcranial Doppler ultrasonography without and with pressure provocation, predicts the need for cerebrospinal fluid drainage in hydrocephalic children. Both without and with pressure provocation, the resistive index was significantly higher (P > 0.05) in patients with raised intracranial pressure compared with control group patients and dropped significantly after drainage. With receiver operating characteristic analysis, the optimal cutoff point between normal and abnormal resistive index values was determined at 0.71 without pressure provocation and at 0.90 with pressure provocation. The addition of the pressure provocation test improved accuracy from 81 to 91%, mainly by improving specificity. In conclusion, transcranial Doppler ultrasonography with pressure provocation accurately identifies hydrocephalic children who require cerebrospinal fluid drainage procedures.

摘要

本研究的目的是确定经颅多普勒超声检查在无压力激发和有压力激发情况下所测得的大脑前动脉阻力指数是否可预测脑积水患儿脑脊液引流的必要性。无论有无压力激发,颅内压升高患者的阻力指数均显著高于对照组患者(P>0.05),且引流后显著下降。通过受试者工作特征分析,确定无压力激发时正常与异常阻力指数值之间的最佳截断点为0.71,有压力激发时为0.90。压力激发试验的加入将准确率从81%提高到91%,主要是通过提高特异性实现的。总之,经颅多普勒超声检查结合压力激发可准确识别需要进行脑脊液引流手术的脑积水患儿。

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