Sato K, Aoki M, Noyori R
Department of Chemistry and Research Center for Materials Science, Nagoya University, Chikusa, Nagoya 464-8602, Japan.
Science. 1998 Sep 11;281(5383):1646-7. doi: 10.1126/science.281.5383.1646.
Currently, the industrial production of adipic acid uses nitric acid oxidation of cyclohexanol or a cyclohexanol/cyclohexanone mixture. The nitrous oxide emission from this process measurably contributes to global warming and ozone depletion. Therefore, the development of an adipic acid production process that is less damaging to the environment is an important subject in chemical research. Cyclohexene can now be oxidized directly to colorless crystalline adipic acid with aqueous 30 percent hydrogen peroxide under organic solvent- and halide-free conditions, which could provide an ideal solution to this serious problem.
目前，己二酸的工业生产采用硝酸氧化环己醇或环己醇/环己酮混合物的方法。该过程中一氧化二氮的排放对全球变暖和臭氧层损耗有显著影响。因此，开发一种对环境危害较小的己二酸生产工艺是化学研究中的一个重要课题。现在，在无有机溶剂和卤化物的条件下，环己烯可以用30%的过氧化氢水溶液直接氧化为无色结晶己二酸，这可能为这个严重问题提供一个理想的解决方案。
