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大屠杀幸存者成年子女患创伤后应激障碍的易感性。

Vulnerability to posttraumatic stress disorder in adult offspring of Holocaust survivors.

作者信息

Yehuda R, Schmeidler J, Wainberg M, Binder-Brynes K, Duvdevani T

机构信息

Department of Psychiatry, Mount Sinai School of Medicine, Bronx VA Medical Center, NY 10468, USA.

出版信息

Am J Psychiatry. 1998 Sep;155(9):1163-71. doi: 10.1176/ajp.155.9.1163.

DOI:10.1176/ajp.155.9.1163
PMID:9734537
Abstract

OBJECTIVE

There has been considerable controversy regarding the impact of the Holocaust on the second generation, but few empirical data are available that systematically document trauma exposure and psychiatric disorder in these individuals. To obtain such data, the authors examined the prevalence of stress and exposure to trauma, current and lifetime posttraumatic stress disorder (PTSD), and other psychiatric diagnoses in a group of adult offspring of Holocaust survivors (N=100) and a demographically similar comparison group (N=44).

METHOD

Subjects were recruited from both community and clinical populations and were evaluated with the use of structured clinical instruments. Stress and trauma history were evaluated with the Antonovsky Life Crises Scale and the Trauma History Questionnaire, PTSD was diagnosed with the Clinician Administered PTSD Scale, and other psychiatric disorders were evaluated according to the Structured Clinical Interview for DSM-IV.

RESULTS

The data show that although adult offspring of Holocaust survivors did not experience more traumatic events, they had a greater prevalence of current and lifetime PTSD and other psychiatric diagnoses than the demographically similar comparison subjects. This was true in both community and clinical subjects.

CONCLUSIONS

The findings demonstrate an increased vulnerability to PTSD and other psychiatric disorders among offspring of Holocaust survivors, thus identifying adult offspring as a possible high-risk group within which to explore the individual differences that constitute risk factors for PTSD.

摘要

目的

关于大屠杀对第二代人的影响一直存在相当大的争议,但很少有实证数据能系统地记录这些人所遭受的创伤暴露和精神障碍情况。为获取此类数据,作者对一组大屠杀幸存者的成年子女(N = 100)以及一个人口统计学特征相似的对照组(N = 44)进行了研究,调查了他们的压力和创伤暴露情况、当前及终生创伤后应激障碍(PTSD)以及其他精神疾病诊断的患病率。

方法

研究对象从社区和临床人群中招募,并使用结构化临床工具进行评估。通过安托诺夫斯基生活危机量表和创伤史问卷评估压力和创伤史,使用临床医生管理的PTSD量表诊断PTSD,根据《精神疾病诊断与统计手册》第四版(DSM-IV)的结构化临床访谈评估其他精神疾病。

结果

数据显示,尽管大屠杀幸存者的成年子女经历的创伤事件并不更多,但与人口统计学特征相似的对照对象相比,他们当前及终生PTSD和其他精神疾病诊断的患病率更高。在社区和临床研究对象中均是如此。

结论

研究结果表明,大屠杀幸存者的后代患PTSD和其他精神疾病的易感性增加,从而确定成年子女是一个可能的高危群体,可在其中探索构成PTSD风险因素的个体差异。

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