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脊髓鞘内放线菌病:一例报告。

Spinal intrathecal actinomycosis: a case report.

作者信息

Ushikoshi S, Koyanagi I, Hida K, Iwasaki Y, Abe H

机构信息

Department of Neurosurgery, University of Hokkaido, School of Medicine, Sapporo, Japan.

出版信息

Surg Neurol. 1998 Sep;50(3):221-5. doi: 10.1016/s0090-3019(97)00183-3.

Abstract

BACKGROUND

Actinomycosis of the central nervous system is a rare disease that most frequently forms cerebral abscesses. In the present report, we describe an extremely rare case of spinal intrathecal actinomycosis.

CASE PRESENTATION

A 33-year-old man presented with high fever followed by back pain and paraparesis. Magnetic resonance imaging (MRI) with gadolinium-diethylene-triamine penta-acetic acid (Gd-DTPA) enhancement (Gd-MRI) displayed an irregularly enhanced mass lesion at the thoraco-lumbar junction that mimicked an intramedullary tumor with exophytic growth. Surgical exploration 7 months after the onset of the high fever revealed intrathecal granulation tissue with small abscess formation. Another surgical exploration was carried out 2 months after the first operation because the patient developed progressive paraparesis and showed an intrathecal ring-like enhancement that was detected with Gd-MRI. Actinomyces organisms were finally identified histologically in the surgical specimen.

CONCLUSIONS

The clinical course and serial changes of Gd-MRI findings are important considerations when this rare and infectious spinal lesion is suspected.

摘要

背景

中枢神经系统放线菌病是一种罕见疾病,最常形成脑脓肿。在本报告中,我们描述了一例极其罕见的脊髓鞘内放线菌病病例。

病例报告

一名33岁男性,先是高热,随后出现背痛和双下肢轻瘫。钆-二乙烯三胺五乙酸(Gd-DTPA)增强磁共振成像(MRI)(Gd-MRI)显示胸腰段交界处有一个不规则强化的肿块病变,类似有外生性生长的髓内肿瘤。高热发作7个月后进行手术探查,发现鞘内肉芽组织并有小脓肿形成。首次手术后2个月,由于患者双下肢轻瘫进展且Gd-MRI检测到鞘内环状强化,故再次进行手术探查。最终在手术标本中通过组织学鉴定出放线菌。

结论

当怀疑存在这种罕见的感染性脊柱病变时,临床病程和Gd-MRI表现的系列变化是重要的考虑因素。

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