麦迪逊-达比犬肾细胞对高渗培养基的适应性：电子微探针分析
Adaptation of Madin-Darby canine kidney cells to hypertonic medium: an electron microprobe analysis.
作者信息
Borgmann S, Dörge A
机构信息
Department of Physiology, University of Munich, Germany.
出版信息
Kidney Int Suppl. 1998 Sep;67:S133-5. doi: 10.1046/j.1523-1755.1998.06725.x.
Abstract
Madin-Darby canine kidney (MDCK) cells of confluent epithelial sheets grown on permeable supports respond to hyperosmotic stress by short- and long-term regulatory volume increase (RVI). Although short-term RVI includes the uptake of inorganic electrolytes, long-term RVI does not and seems therefore to result from accumulation of organic osmolytes.
摘要
在可渗透支持物上生长的汇合上皮片的犬肾传代细胞（MDCK细胞）通过短期和长期调节性容积增加（RVI）对高渗应激作出反应。虽然短期RVI包括无机电解质的摄取，但长期RVI并非如此，因此似乎是由有机渗透溶质的积累导致的。
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