Hulse R K, Clark S J, Jackson J C, Warner H R, Gardner R M
Am J Hosp Pharm. 1976 Oct;33(10):1061-4.
A computerized medication monitoring system for alerting and warning of potential adverse drug reactions is described. The system integrates computerized data on each hospital patient (medications, clinical laboratory, blood gas, ECG, ALLERGIES, DIAGNOSIs, etc.) and returns to the pharmacist warning messages and suggestions regarding patient drug therapy. The broad data base allows for nearly complete drug therapy monitoring. When a warning message is received, the pharmacist contacts the physician or nursing staff and explains the potential problem. The system also generates prescription labels and patient drug profiles which are used in a unit dose dispensing system. Five percent of 13,727 patients monitored have had drug alerts. Of these alterts, 44.9% were drug-laboratory contraindications and only 28.9% were drug-drug interactions. Of the 690 alerts received, 77% resulted in the physician changing the patient's therapy.
描述了一种用于提醒和警告潜在药物不良反应的计算机化药物监测系统。该系统整合了每位医院患者的计算机化数据(药物、临床实验室检查、血气、心电图、过敏史、诊断等),并向药剂师返回有关患者药物治疗的警告信息和建议。广泛的数据库允许对药物治疗进行几乎全面的监测。当收到警告信息时,药剂师会联系医生或护理人员并解释潜在问题。该系统还生成用于单剂量配药系统的处方标签和患者药物档案。在监测的13727名患者中,有5%收到了药物警报。在这些警报中,44.9%是药物与实验室检查结果的禁忌情况,只有28.9%是药物相互作用。在收到的690条警报中,77%导致医生改变了患者的治疗方案。