Wada Y, Jimi A, Nakashima O, Kojiro M, Kurohiji T, Sai K
First Department of Pathology, Kurume University School of Medicine, Fukuoka, Japan.
Pathol Int. 1998 Aug;48(8):611-7. doi: 10.1111/j.1440-1827.1998.tb03958.x.
Two surgical cases of benign schwannoma of the liver were examined: A 64-year-old female who was admitted to hospital for the treatment of early gastric cancer (case 1) and a 69-year-old female who had pitting edema in the legs (case 2). Diagnostic imaging revealed large solid masses located in the caudate lobe through to the left lobe of the liver in case 1 and in the left lobe in case 2. Both patients showed no signs of von Recklinghausen's disease. Partial hepatectomies were performed and the maximum diameter of their resected hepatic tumors was 4 cm and 15 cm, respectively. Histologically, the well-demarcated tumors were yellowish in color, elastic-hard in consistency and consisted predominantly of short spindle-shaped cells proliferating in an interlacing fashion. The tumor lesions were separated by fibrous bands and surrounded by a lymphoid cuff. Immunohistochemically, the tumor cells were positive for S-100 protein. The tumors were diagnosed as benign hepatic schwannoma.
一例为64岁女性，因早期胃癌入院治疗（病例1）；另一例为69岁女性，有腿部凹陷性水肿（病例2）。诊断性影像学检查显示，病例1的巨大实性肿块位于肝脏尾状叶至左叶，病例2的肿块位于左叶。两名患者均无冯雷克林霍增氏病的体征。两位患者均接受了肝部分切除术，切除的肝肿瘤最大直径分别为4厘米和15厘米。组织学上，边界清晰的肿瘤呈淡黄色，质地弹性硬，主要由短梭形细胞以交织方式增殖组成。肿瘤病变被纤维带分隔，并被淋巴样套袖包围。免疫组化显示，肿瘤细胞S-100蛋白呈阳性。这些肿瘤被诊断为肝脏良性神经鞘瘤。
