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原发性肝神经鞘瘤:一例报告。

Primary hepatic schwannoma: A case report.

作者信息

Yamamoto Masaki, Hasegawa Kiyoshi, Arita Junichi, Maeno Ryohei, Akamatsu Nobuhisa, Kaneko Junichi, Watadani Takeyuki, Okura Naoki, Hayashi Akimasa, Shibahara Junji, Sakamoto Yoshihiro, Ohtomo Kuni, Fukayama Masashi, Kokudo Norihiro

机构信息

Hepato-Biliary-Pancreatic Surgery Division and Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

Hepato-Biliary-Pancreatic Surgery Division and Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

出版信息

Int J Surg Case Rep. 2016;29:146-150. doi: 10.1016/j.ijscr.2016.11.009. Epub 2016 Nov 9.

Abstract

INTRODUCTION

A hepatic schwannoma is extremely rare and difficult to diagnose preoperatively.

PRESENTATION OF CASE

We report the case of a 47-year-old male patient who was referred to our hospital for the close investigation of a hepatic tumor which had not been detected two years earlier. An enhanced computed tomography revealed a well-circumscribed and encapsulated tumor with a size of 50mm which was adjacent to the inferior vena cava (IVC) and the right hepatic vein. The tumor was heterogeneously enhanced until the equilibrium phase. A magnetic resonance image showed a hypointense area on a T1-weighted image and a hyperintense area on a T2-weighted image. These findings differed from those of common malignant hepatic tumors, such as hepatocellular carcinoma and colorectal liver metastases. The tumor was most likely a mucus-producing tumor or a liquefactive degenerated adenocarcinoma. Although we could not confirm an exact diagnosis of the tumor, we performed a surgical resection in view of the possibility of malignancy. The patient underwent a limited liver resection with resection of the IVC. Histologically, the tumor was diagnosed as a benign schwannoma comprised of Antoni A and B areas. The nuclear palisading formation of the tumor showed Verocay bodies.

DISCUSSION

15 cases of hepatic schwannoma are reviewed to clarify the typical radiological features. The radiological findings of the present case were consistent with those of the hepatic schwannoma when considering retrospectively.

CONCLUSION

A precise preoperative diagnosis of hepatic schwannoma is difficult, and liver resection is recommended when a hepatic schwannoma is suspected.

摘要

引言

肝神经鞘瘤极为罕见,术前难以诊断。

病例介绍

我们报告一例47岁男性患者,因对两年前未检测到的肝脏肿瘤进行密切检查而转诊至我院。增强计算机断层扫描显示一个边界清晰、有包膜的肿瘤,大小为50mm,毗邻下腔静脉(IVC)和右肝静脉。肿瘤在平衡期前呈不均匀强化。磁共振成像显示在T1加权图像上为低信号区,在T2加权图像上为高信号区。这些表现与常见的恶性肝脏肿瘤,如肝细胞癌和结直肠癌肝转移不同。该肿瘤很可能是黏液产生性肿瘤或液化性退变腺癌。尽管我们无法确诊该肿瘤,但鉴于其恶性可能性,我们进行了手术切除。患者接受了包括切除IVC的有限肝切除术。组织学上,肿瘤被诊断为良性神经鞘瘤,由Antoni A区和B区组成。肿瘤的核栅栏状排列形成了Verocay小体。

讨论

回顾了15例肝神经鞘瘤病例以明确其典型的放射学特征。回顾性考虑时,本病例的放射学表现与肝神经鞘瘤相符。

结论

肝神经鞘瘤术前难以精确诊断,怀疑为肝神经鞘瘤时建议行肝切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c33b/5114688/75e63a932dd0/gr1.jpg

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