Westphal S A
Department of Medicine, Maricopa Medical Center, Phoenix, Arizona, USA.
Mayo Clin Proc. 1998 Sep;73(9):893-4. doi: 10.4065/73.9.893.
This article describes a patient in whom disseminated infection with coccidioidomycosis was associated with hypercalcemia. The patient had a low level of 1,25-dihydroxyvitamin D and a suppressed parathyroid hormone value, an indication that the hypercalcemia was not mediated by vitamin D or parathyroid hormone. The episode resolved readily with administration of pamidronate, an outcome suggesting that this is effective treatment of hypercalcemia of this origin. On follow-up of the patient while he was receiving antifungal therapy for Coccidioides immitis, calcium values remained normal.
本文描述了一名播散性球孢子菌病感染患者，其伴有高钙血症。该患者1,25 - 二羟维生素D水平较低，甲状旁腺激素值受到抑制，这表明高钙血症并非由维生素D或甲状旁腺激素介导。给予帕米膦酸后病情迅速缓解，这一结果表明这是治疗该病因所致高钙血症的有效方法。在患者接受针对粗球孢子菌的抗真菌治疗期间进行随访时，血钙值保持正常。
