Sargent E V, Brubaker R E, Mitchell C A
Arch Environ Health. 1976 Sep-Oct;31(5):236-40. doi: 10.1080/00039896.1976.10667226.
A standardized respiratory questionnaire and pulmonary function tests were used to examine thirty-four employees of a snow-ski manufacturing plant, including twenty-five workers who were exposed to an epoxy resin system containing the amine hardener 3-dimethylamino propylamine (3-DMAPA). Maximum expiratory flow-volume curves were obtained on Monday and Thursday, before and after each shift, and FVC, FEV1.0, MEF50%, and MEF25% were caculated. Environmental measurements of the total amine levels were found to range from 0.41 to 1.38 ppm. The group with the greatest exposure (0.55-1.38 ppm) showed significant decreases in lung function over Monday and over the week. Although all employees in this group showed decreases in pulmonary function, acute changes were greater in present cigarette smokers and in subjects who reported respiratory symptoms upon exposure to the epoxy resin system. There was no evidence of permanent loss of lung function in subjects with either the highest or longest exposure.
采用标准化呼吸问卷和肺功能测试对一家滑雪板制造工厂的34名员工进行检查，其中包括25名接触含有胺类固化剂3-二甲基氨基丙胺（3-DMAPA）的环氧树脂体系的工人。在周一和周四每个班次前后获取最大呼气流量-容积曲线，并计算用力肺活量（FVC）、第1秒用力呼气容积（FEV1.0）、50%最大呼气流量（MEF50%）和25%最大呼气流量（MEF25%）。环境中总胺水平的测量结果显示范围为0.41至1.38 ppm。暴露程度最高（0.55 - 1.38 ppm）的组在周一以及整个一周内肺功能出现显著下降。尽管该组所有员工的肺功能都有所下降，但当前吸烟者以及报告在接触环氧树脂体系时有呼吸道症状的受试者的急性变化更大。无论是暴露程度最高还是暴露时间最长的受试者，均未发现有肺功能永久性丧失的证据。
