Rempel D, Jones J, Atterbury M, Balmes J
Center for Occupational and Environmental Health, University of California, San Francisco.
Br J Ind Med. 1991 Nov;48(11):783-7. doi: 10.1136/oem.48.11.783.
Epoxy resin systems have been associated with occupational asthma in several case reports, but medical publications contain little on the potential adverse respiratory effects of these chemicals in exposed worker populations. To further evaluate the association of workplace exposure to epoxy paints and respiratory dysfunction, the cross workshift changes in pulmonary function and symptoms of 32 shipyard painters exposed to epoxy paints were compared with 28 shipyard painters not exposed to epoxy paints. The prevalence of lower respiratory tract symptoms was significantly higher among painters exposed to epoxy paints compared with controls. Among exposed painters the mean cross workshift change in forced expiratory volume in one second (FEV1) (-3.4%) was greater than the decrement in the non-exposed group (-1.4%). A significant linear relation was seen between % decrement in FEV1 and hours of exposure to epoxy paints. This study suggests that epoxy resin coatings as used by shipyard painters are associated with increased lower respiratory tract symptoms and acute decrements in FEV1. Adequate respiratory protection and medical surveillance programmes should be established in workplaces where exposure to epoxy resin systems occurs.
在多篇病例报告中,环氧树脂系统已被证实与职业性哮喘有关,但医学出版物中关于这些化学物质对接触工人呼吸系统潜在不良影响的内容却很少。为了进一步评估工作场所接触环氧漆与呼吸功能障碍之间的关联,对32名接触环氧漆的造船厂油漆工的肺功能和症状的跨工作班次变化与28名未接触环氧漆的造船厂油漆工进行了比较。与对照组相比,接触环氧漆的油漆工下呼吸道症状的患病率明显更高。在接触环氧漆的油漆工中,一秒用力呼气量(FEV1)的平均跨工作班次变化(-3.4%)大于未接触组(-1.4%)。FEV1下降百分比与接触环氧漆的时长之间存在显著的线性关系。这项研究表明,造船厂油漆工使用的环氧树脂涂料与下呼吸道症状增加和FEV1急性下降有关。在存在接触环氧树脂系统的工作场所,应建立充分的呼吸防护和医疗监测计划。