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Bacterial colonization of the upper respiratory tract of patients with primary lung cancer and nonmalignant lung disease.原发性肺癌和非恶性肺部疾病患者上呼吸道的细菌定植
Chemotherapy. 1997 Nov-Dec;43(6):400-5. doi: 10.1159/000239598.
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Genetic relationship of penicillin resistant Streptococcus pneumoniae serotype 19B strains in Japan.日本青霉素耐药19B型肺炎链球菌菌株的遗传关系。
Epidemiol Infect. 1997 Apr;118(2):105-10. doi: 10.1017/s0950268896007273.
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Multifocal outbreaks of metallo-beta-lactamase-producing Pseudomonas aeruginosa resistant to broad-spectrum beta-lactams, including carbapenems.对包括碳青霉烯类在内的广谱β-内酰胺耐药的产金属β-内酰胺酶铜绿假单胞菌的多灶性暴发。
Antimicrob Agents Chemother. 1996 Feb;40(2):349-53. doi: 10.1128/AAC.40.2.349.
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Comparative evaluation of an automated ribotyping system versus pulsed-field gel electrophoresis for epidemiological typing of clinical isolates of Escherichia coli and Pseudomonas aeruginosa from patients with recurrent gram-negative bacteremia.对自动核糖体分型系统与脉冲场凝胶电泳用于复发性革兰氏阴性菌血症患者临床分离的大肠杆菌和铜绿假单胞菌进行流行病学分型的比较评估。
Diagn Microbiol Infect Dis. 1996 May;25(1):1-8. doi: 10.1016/0732-8893(96)00082-x.
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Assessment of clinical significance of positive blood cultures of relatively low-virulence isolates.低毒力分离株血培养阳性的临床意义评估。
J Med Microbiol. 1996 Mar;44(3):195-8. doi: 10.1099/00222615-44-3-195.
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DNA fingerprinting of Streptococcus pneumoniae strains by pulsed-field gel electrophoresis.通过脉冲场凝胶电泳对肺炎链球菌菌株进行DNA指纹图谱分析。
J Clin Microbiol. 1993 Oct;31(10):2724-8. doi: 10.1128/jcm.31.10.2724-2728.1993.
7
Molecular epidemiology of coagulase-negative Staphylococcus blood isolates from neonates with persistent bacteremia and children with central venous catheter infections.来自患有持续性菌血症的新生儿和患有中心静脉导管感染的儿童的凝固酶阴性葡萄球菌血培养分离株的分子流行病学
J Infect Dis. 1994 Jun;169(6):1393-7. doi: 10.1093/infdis/169.6.1393.
8
Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.解读脉冲场凝胶电泳产生的染色体DNA限制性图谱：细菌菌株分型标准
J Clin Microbiol. 1995 Sep;33(9):2233-9. doi: 10.1128/jcm.33.9.2233-2239.1995.
9
The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. I. Laboratory and epidemiologic observations.血培养阳性的临床意义：对500例成人菌血症和真菌血症病例的综合分析。I. 实验室及流行病学观察
Rev Infect Dis. 1983 Jan-Feb;5(1):35-53. doi: 10.1093/clinids/5.1.35.
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Gram-negative pathogens in septicaemic infections.败血症感染中的革兰氏阴性病原体。
Scand J Infect Dis Suppl. 1982;31:78-94.

通过脉冲场凝胶电泳确定菌血症患者血液和非血液分离株之间的遗传关系。

Genetic relationship between blood and nonblood isolates from bacteremic patients determined by pulsed-field gel electrophoresis.

作者信息

Matsuda J, Hirakata Y, Iori F, Mochida C, Ozaki Y, Nakano M, Izumikawa K, Yamaguchi T, Yoshida R, Miyazaki Y, Maesaki S, Tomono K, Yamada Y, Kohno S, Kamihira S

机构信息

Department of Laboratory Medicine, Nagasaki University School of Medicine, Nagasaki 852-8501, Japan.

出版信息

J Clin Microbiol. 1998 Oct;36(10):3081-4. doi: 10.1128/JCM.36.10.3081-3084.1998.

DOI:10.1128/JCM.36.10.3081-3084.1998
PMID:9738076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC105120/
Abstract

A total of 148 isolates from 55 bacteremic patients were examined by pulsed-field gel electrophoresis. Genetically different nonblood strains were isolated from 13.9% of patients with bacteremia caused by gram-positive cocci and 42.1% with Pseudomonas aeruginosa bacteremia, indicating that antibiograms of a single nonblood P. aeruginosa isolate are not always informative for treatment of bacteremia.

摘要

通过脉冲场凝胶电泳对来自55名菌血症患者的总共148株分离菌进行了检测。在由革兰氏阳性球菌引起菌血症的患者中，13.9%分离出了基因不同的非血液菌株；在铜绿假单胞菌菌血症患者中，42.1%分离出了基因不同的非血液菌株，这表明单一非血液铜绿假单胞菌分离株的抗菌谱对于菌血症治疗并不总是具有指导意义。