非洲爪蟾钙黏蛋白-11在不同群迁移的神经嵴细胞中表达。
Xenopus cadherin-11 is expressed in different populations of migrating neural crest cells.
作者信息
Vallin J, Girault J M, Thiery J P, Broders F
机构信息
Laboratoire de Morphogenèse Cellulaire et Progression Tumorale, UMR 144, CNRS/Institut Curie, 26 rue d'Ulm, 75248, Paris Cedex 05, France.
出版信息
Mech Dev. 1998 Jul;75(1-2):171-4. doi: 10.1016/s0925-4773(98)00099-9.
We cloned the Xenopus homologue of cadherin-11 and studied its spatiotemporal expression pattern during early development. The messenger RNA is present from the mid-gastrulation through embryo development. It is expressed in different neural crest cell populations, during their migration and differentiation. This pattern, unexpected for an adhesion molecule, reinforces the idea of novel functions for type II cadherins.
我们克隆了钙黏蛋白-11的非洲爪蟾同源物，并研究了其在早期发育过程中的时空表达模式。从原肠胚中期到胚胎发育阶段都存在信使核糖核酸。它在不同的神经嵴细胞群体迁移和分化过程中表达。这种模式对于一种黏附分子来说出乎意料，强化了II型钙黏蛋白具有新功能的观点。
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