Jahns R, Kenn W, Stolte M, Inselmann G
Medizinische Poliklinik, University of Würzburg, Germany.
Ann Oncol. 1998 Jul;9(7):775-8. doi: 10.1093/oxfordjournals.annonc.a010995.
The case of a 66-year-old woman with a primary cardiac osteosarcoma is described. These distinctly rare malignant tumors arise preferentially in the left atrium. Clinically, they often present symptoms of both, intramural and intracavitary neoplasm in addition to general weakness, recurrent breast pain, and dyspnea. As shown in the present case, with growing intracavitary tumor masses the risk for peripheral arterial including cerebral embolism increases. Consequently, in most patients with symptoms of systemic arterial embolism of unknown origin performance of transesophageal echocardiography seems advisible, which is presently the most convenient noninvasive imaging method to exclude or to identify intracardiac sources of emboli, irrespective of their type.
本文描述了一例66岁原发性心脏骨肉瘤女性患者的病例。这些极为罕见的恶性肿瘤多发生于左心房。临床上,除全身乏力、反复胸痛和呼吸困难外,它们常表现出壁内和腔内肿瘤的症状。如本病例所示,随着腔内肿瘤肿块的增大,包括脑栓塞在内的外周动脉栓塞风险增加。因此,对于大多数有不明原因的系统性动脉栓塞症状的患者,行经食管超声心动图检查似乎是可取的,目前这是排除或识别心内栓子来源最便捷的无创成像方法,无论栓子类型如何。