Granel F, Truchetet F, Grandidier M
Service de Dermatologie, CHR Metz Thionville, Hôpital Beauregard, Thionville.
Ann Dermatol Venereol. 1997;124(6-7):460-2.
Nail dyschromia in patients infected with human immunodeficiency virus (HIV) was first described in 1987 by Furth and Kazakis. It has since been reported in patients with the acquired immunodeficiency syndrome (AIDS), predominantly in patients treated with zidovudine.
We describe the case of a 37 years old white woman, who developed AIDS in 1994, with nail longitudinal colored bands, oral and cutaneous pigmentation without taking zidovudine.
There have been four reports of nail pigmentation in HIV-infected patients who had no received this antiviral agent. The singularity of our case is the onset in a white woman. A lot of causes must be evoked and biology must be done, with histopathologic study when it is possible.
1987年，弗思（Furth）和卡扎基斯（Kazakis）首次描述了感染人类免疫缺陷病毒（HIV）患者的指甲色素沉着异常。此后，在获得性免疫缺陷综合征（AIDS）患者中也有相关报道，主要发生在接受齐多夫定治疗的患者身上。
我们描述了一名37岁白人女性的病例，她于1994年患上艾滋病，出现指甲纵向色带、口腔和皮肤色素沉着，且未服用齐多夫定。
有4篇关于未接受这种抗病毒药物治疗的HIV感染患者指甲色素沉着的报告。我们这个病例的独特之处在于发病者为一名白人女性。必须考虑多种病因，并进行生物学检查，可能的话还需进行组织病理学研究。
