Wacker J, Schulz M, Frühauf J, Chiwora F M, Solomayer E, Bastert G
Universitäts-Frauenklinik Heidelberg, University of Heidelberg, Germany.
Acta Obstet Gynecol Scand. 1998 Aug;77(7):712-6.
The aim of our study was to evaluate the number of women with hypertensive complications during pregnancy in a southern province in Zimbabwe and to examine the annual change in the incidence of preeclampsia.
In three different hospitals the preeclamptic women who were treated between January 1992 and August 1995 were counted. This data was compared with the amount of rainfall obtained from the local meteorological stations.
A distinctive change in the incidence of preeclampsia during the year could be observed. These changes go along with the seasonal variation in precipitation: at the end of the dry season and in the first months of the rainy season there is an increase in the incidence.
The relationship between climate and occurrence of preeclampsia raises new questions in the pathophysiology of preeclampsia. Possible explanations could be the impact of humidity and temperature on vessels or the production of vasoactive substances. Dry and rainy seasons influence the agricultural yields and therefore the nutritional status could also play a role in the pathophysiology.
我们研究的目的是评估津巴布韦南部某省孕期发生高血压并发症的女性数量,并调查子痫前期发病率的年度变化。
统计了1992年1月至1995年8月期间在三家不同医院接受治疗的子痫前期女性。将该数据与当地气象站获取的降雨量进行比较。
可以观察到子痫前期发病率在一年中存在明显变化。这些变化与降水的季节变化一致:在旱季末和雨季的头几个月发病率会增加。
气候与子痫前期发生之间的关系为子痫前期的病理生理学提出了新问题。可能的解释是湿度和温度对血管的影响或血管活性物质的产生。旱季和雨季影响农作物产量,因此营养状况在病理生理学中也可能起作用。