Díaz G F, Virués T, San Martín M, Ruiz M, Galán L, Paz L, Valdés P
Cuban Center for Neurosciences, Havana.
Electroencephalogr Clin Neurophysiol. 1998 Jun;106(6):501-7. doi: 10.1016/s0013-4694(98)00026-1.
Spectral features of EEG background activity were studied in patients with localized symptomatic epilepsy (LSE), with origin in the frontal or temporal lobes. Z-values of high resolution spectra and measures of the parametric (xi alpha) model of the EEG were obtained for all 10/20 System leads and were compared with those obtained in a control group. Comparisons were performed between syndromic variants of LSE and between subgroups of patients with or without paroxysmal activity in their digital EEGs (dEEG). Marked reduction of the energy in the alpha range and a mild increase in the theta range were found in the patients, unrelated to the syndromic variant of the epilepsy. These deviations from normality were widespread on the scalp and were not related to antiepileptic medication. Non-parametric testing showed a positive correlation between the magnitude of the quantitative EEG abnormalities and the amount of paroxysmal activity in the dEEG. Slowing of the mean frequency of alpha components of the spectra, an actual decrease of power in the alpha range and an increase in the theta range explained the results. The most striking finding of this paper is that focal epileptogenesis may have a generalized impact in the frequency composition of EEG.
对起源于额叶或颞叶的局限性症状性癫痫（LSE）患者的脑电图背景活动的频谱特征进行了研究。获取了所有10/20系统导联的高分辨率频谱的Z值和脑电图参数（xi alpha）模型的测量值，并与对照组的测量值进行比较。在LSE的综合征变体之间以及数字脑电图（dEEG）中有或无阵发性活动的患者亚组之间进行了比较。在患者中发现α频段能量明显降低，θ频段轻度增加，这与癫痫的综合征变体无关。这些与正常情况的偏差在头皮上广泛存在，且与抗癫痫药物无关。非参数检验显示，定量脑电图异常的程度与dEEG中的阵发性活动量之间存在正相关。频谱α成分平均频率减慢、α频段功率实际降低以及θ频段增加解释了这些结果。本文最显著的发现是局灶性癫痫发生可能对脑电图的频率组成产生全身性影响。
