Ioakim P, Rosen D
Biomed Eng. 1976 Oct;11(10):351-3.
A system is proposed for haemodialysis which involves both dialysis and adsorption. The blood compartment is separated by a membrane from a compartment containing adsorbents and ion exchangers under reduced pressure. Urea is broken down by urease adsorbed on an ion exchanger. The ammonia produced is pumped out and the rest of the unwanted substances are bound to the adsorbing materials. The geometry and principles governing the operation of the device obviate the use of circulating dialysate fluid. Preliminary results from in vitro experiments with such a system are reported and the possibility of using this system clinically is discussed.
提出了一种用于血液透析的系统，该系统涉及透析和吸附。血液腔室通过膜与在减压下含有吸附剂和离子交换剂的腔室分隔开。尿素被吸附在离子交换剂上的脲酶分解。产生的氨被泵出，其余不需要的物质则与吸附材料结合。该装置的几何结构和运行原理避免了使用循环透析液。报告了使用这种系统进行体外实验的初步结果，并讨论了在临床上使用该系统的可能性。
