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[一例经手术切除的纵隔肿块,组织学证实为呈现髓外造血并伴有地中海贫血的肿块样组织]

[A case of surgically resected mediastinal mass histologically proven to be a mass-like tissue presenting extramedullary hematopoiesis accompanied by thalassemia].

作者信息

Morita H, Yoshimura H

机构信息

Department of Thoracic Surgery, Kawasaki Kyodo Hospital, Japan.

出版信息

Kyobu Geka. 1998 Jul;51(8 Suppl):713-5.

PMID:9742809
Abstract

We experienced with a case showing a mediastinal mass on chest X-ray accompanied by thalassemia. Preoperative diagnosis for this mass was a neulogenic tumor based on the findings of roentgenogram. Surgical resection of the mass was performed, and histology revealed that it was a mass-like tissue presenting extramedullary hematopoiesis. Generally speaking, any tissues functioning as extramedullary hematopoiesis should not be resected in patients with anemia or showing bone marrow suppression. And it is also said that 111In-chloride scintigram is highly diagnostic for patients with a tissue functioning as extramedullary hematopoiesis. We had not performed 111In-chloride scintigram for this case preoperatively and performed a resection of the mediastinal mass carelessly. Care should be taken not to perform surgical resection carelessly in cases with a mediastinal mass accompanied by anemia or bone marrow suppression.

摘要

我们遇到过一例胸部 X 光显示纵隔肿块且伴有地中海贫血的病例。根据 X 光检查结果,该肿块术前诊断为神经源性肿瘤。对该肿块进行了手术切除,组织学检查显示它是一种呈现髓外造血的肿块样组织。一般来说,对于贫血或有骨髓抑制表现的患者,任何具有髓外造血功能的组织都不应切除。据说,氯化铟 - 111 闪烁扫描对具有髓外造血功能的组织的患者具有高度诊断价值。我们术前未对该病例进行氯化铟 - 111 闪烁扫描,就贸然对纵隔肿块进行了切除。对于伴有贫血或骨髓抑制的纵隔肿块病例,应注意避免贸然进行手术切除。

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