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使用多普勒超声技术测量指动脉压而不进行血管痉挛测试以检测指动脉闭塞是否合理?

Does the measurement of digital arterial pressure using the Doppler ultrasonic technique without testing for vasospasm to detect digital arterial occlusions make good sense?

作者信息

Heidrich H, Blank B

机构信息

Department of Internal Medicine, Franziskus-Krankenhaus, Berlin, Germany.

出版信息

Vasa. 1998 Aug;27(3):158-62.

PMID:9747151
Abstract

BACKGROUND

An attempt was made to determine whether measurement of the systolic pressure with the Doppler ultrasonic technique can be used to detect occlusions of the digital arteries.

PATIENTS AND METHODS

A total of 92 patients (44 women, 48 men) with an average age of 47.5 years (range: 19-82 years) were investigated. Of these, 17 were diagnosed with a primary Raynaud's syndrome, 45 with a secondary, and 5 patients with a suspected secondary Raynaud's syndrome; 25 patients had digital occlusions of varying genesis. In all patients, the Doppler ultrasonic technique was applied to measure the systolic pressure of the digital arteries of both hands at a room temperature of 21-24 degrees Celsius without any additional thermal (warm or cold) provocation or use of vasodilatory agents; the results obtained were compared with arteriographs of the hands.

RESULTS

While the sensitivity of the Doppler ultrasonic technique was a very low 55%, the specificity was a very high 95%. With a prevalence of 68%, the positive predictive value was 96%, the negative predictive value 50%. In the case of angiographically patent digital arteries with no spastic narrowing, the Doppler ultrasonic-measured systolic pressure was up to 30 mmHg above, and up to 25 mmHg below, the systolic pressure measured in the ipsilateral brachial artery. A pressure gradient between upper arm and digital arteries of this order of magnitude therefore does not exclude pathological changes. Only angiography was able reliably to detect vascular stenoses and occlusions.

CONCLUSION

Reliable exclusion of digital arterial occlusions using the Doppler ultrasonic technique without testing for vasospasm is not possible. Only occlusions of digital arteries together with simultaneous occlusions of hand arteries can be reliably detected. Owing to the considerable scatter of the systolic blood pressure gradient between brachial and digital arteries, the Doppler ultrasonic technique cannot be used to distinguish between patent and occluded digital arteries without the use of additional vasodilation.

摘要

背景

尝试确定使用多普勒超声技术测量收缩压是否可用于检测指动脉闭塞。

患者与方法

共对92例患者(44例女性,48例男性)进行了研究,平均年龄47.5岁(范围:19 - 82岁)。其中,17例被诊断为原发性雷诺综合征,45例为继发性,5例疑似继发性雷诺综合征;25例患者存在不同病因的指动脉闭塞。所有患者均在21 - 24摄氏度室温下,未进行任何额外的热(温热或寒冷)激发或使用血管扩张剂的情况下,应用多普勒超声技术测量双手指动脉的收缩压;将所得结果与手部动脉造影结果进行比较。

结果

虽然多普勒超声技术的敏感性非常低,仅为55%,但其特异性非常高,为95%。在患病率为68%的情况下,阳性预测值为96%,阴性预测值为50%。在血管造影显示指动脉通畅且无痉挛性狭窄的情况下,多普勒超声测量的收缩压比同侧肱动脉测量的收缩压高出多达30 mmHg,低至25 mmHg。因此,上臂与指动脉之间这种量级的压力梯度并不能排除病理变化。只有血管造影能够可靠地检测血管狭窄和闭塞。

结论

在不进行血管痉挛检测的情况下,使用多普勒超声技术无法可靠地排除指动脉闭塞。只有指动脉闭塞同时伴有手部动脉闭塞时才能可靠检测。由于肱动脉和指动脉之间收缩压梯度存在相当大的离散度,在不使用额外血管扩张的情况下,多普勒超声技术无法用于区分指动脉通畅和闭塞情况。

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