Spenatto N, Marguery M C, el Sayed F, Montazeri A, Bazex J
Service de Dermatologie, Hôpital Purpan, Toulouse.
Ann Dermatol Venereol. 1998 Jan;125(1):27-9.
A case of photosensitive prurigo during AIDs is reported. This is the second case in the literature. We discuss the relations between HIV infection and photodermatoses.
A woman, known to be HIV seropositive from 1990, developed during the spring 1990 a prurigo on light exposed areas who received the next year. A photobiological investigation was performed, showing a polymorphic light eruption induced by UVB.
Patients infected with HIV have a high prevalence of UV radiation responsive skin diseases. On the other hand, UVA radiations, UVB and UVC have been shown to induce activation and replication of HIV. PUVA therapy and UVB therapy have shown their efficacity in the treatment of many photodermatoses associated with HIV infection, without any worsening of the illness. Many questions are not yet solved in the relationship between HIV and photosensitivity and the photobiological investigation should be more frequently done.
报告了1例艾滋病期间发生的光敏性痒疹病例。这是文献中的第二例。我们讨论了HIV感染与光皮肤病之间的关系。
一名自1990年起已知HIV血清学阳性的女性,于1990年春季在光照部位出现痒疹,次年接受了光生物学检查,结果显示为由中波紫外线诱发的多形性日光疹。
感染HIV的患者中对紫外线辐射有反应的皮肤病患病率很高。另一方面,已证明长波紫外线、中波紫外线和短波紫外线可诱导HIV激活和复制。补骨脂素紫外线A疗法和中波紫外线疗法已显示出对许多与HIV感染相关的光皮肤病有治疗效果,且病情无任何恶化。HIV与光敏性之间的关系仍有许多问题尚未解决,应更频繁地进行光生物学检查。