Léauté-Labrèze C, Gautier C, Labbé L, Taieb A
Unité de Dermatologie Pédiatrique, Hôpital Pellegrin-Enfants, Bordeaux.
Ann Dermatol Venereol. 1998 Feb;125(2):132-4.
We report a case of severe infantile cystic acne, which required a treatment with oral isotretinoin.
The patient, a 22-month-old boy, presented cystic acne since 6 months of age. The child was otherwise healthy and endocrine evaluation was normal. Previous treatments had no effect, oral isotretinoine led to cure without secondary effects.
The etiology of infantile acne is not clearly defined, but may result from a persisting androgen-driven stimulation of sebaceous glands. Oral isotretinoin is safe and effective in case of recalcitrant infantile acne, but close monitoring is necessary because of the well-known side effects of oral retinoids.
我们报告一例严重婴儿囊性痤疮病例,该病例需要口服异维A酸进行治疗。
患者为一名22个月大的男孩,自6个月大起出现囊性痤疮。该患儿其他方面健康,内分泌评估正常。先前的治疗无效,口服异维A酸治愈且无继发效应。
婴儿痤疮的病因尚不明确,但可能是由于雄激素持续刺激皮脂腺所致。对于顽固性婴儿痤疮,口服异维A酸安全有效,但由于口服维甲酸类药物众所周知的副作用,需要密切监测。