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[低温状态下心脏的功能活动、能量代谢与存活]

[The functional activity, energetics and survival of the heart under hypothermia].

作者信息

Aliukhin Iu S

机构信息

Institute of Physiology named after I. P. Pavlov, Russian Academy of Sciences, St. Petersburg.

出版信息

Usp Fiziol Nauk. 1998 Jul-Sep;29(3):66-78.

PMID:9749458
Abstract

Adequate blood supply to tissue, which is the most important prerequisite for survival of the organisms when put under hypothermal conditions and taken out of these conditions depends, above all, on the cardial function. Detailed exploration of the automatic reactions, response to stimulation, conductivity and systole of hypothermal cardium using a cardio-pulmonary preparation has been reported by V. M. Pokrovskiĭ and co-authors. As far as we are informed, this monographic volume is the only available review of developments in the last decades in studies of cardium under hypothermal conditions. In this article we shall touch upon the issues not covered by the above monograph including energy status of hypothermal cardium and the issues important the physiological and medical perspectives: cardium functional status in situ under accidental hypothermal conditions (hypothermal freezing), and maintaining functionality of cardium after its stoppage in hypothermal conditions.

摘要

组织的充足血液供应是生物体在低温条件下生存的最重要前提,而在脱离这些条件时,这首先取决于心脏功能。V. M. 波克罗夫斯基及其合著者报告了使用心肺制剂对低温心脏的自动反应、对刺激的反应、传导性和收缩进行的详细探索。据我们所知,这本专著是过去几十年来低温条件下心脏研究进展的唯一可用综述。在本文中,我们将探讨上述专著未涵盖的问题,包括低温心脏的能量状态以及从生理和医学角度来看重要的问题:意外低温条件下(低温冻伤)原位心脏的功能状态,以及心脏在低温条件下停止跳动后的功能维持。

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