Hunter B C, Devaney K O, Ferlito A, Rinaldo A
Department of Pathology, University of Michigan, Ann Arbor, USA.
Ann Otol Rhinol Laryngol. 1998 Sep;107(9 Pt 1):810-4. doi: 10.1177/000348949810700914.
Alveolar soft part sarcoma is a soft tissue malignancy most often found in the extremities of young adults; when these tumors arise in the head and neck area, they usually appear in the orbit or the tongue. Their initial behavior is relatively indolent, but over time a sizable number of these tumors recur locally and metastasize; as such, they are best regarded as fully malignant neoplasms. The derivation of these tumors remains uncertain: while some have suggested that these are tumors of muscle origin and others have postulated a neuroendocrine origin, the evidence accumulated to date is conflicting, and so these neoplasms continue to be regarded as tumors of uncertain origin. Surgical excision is the mainstay of therapy.
肺泡软组织肉瘤是一种软组织恶性肿瘤，最常见于年轻成年人的四肢；当这些肿瘤发生在头颈部区域时，通常出现在眼眶或舌头。它们最初的行为相对惰性，但随着时间的推移，相当数量的这些肿瘤会局部复发并转移；因此，它们最好被视为完全恶性肿瘤。这些肿瘤的起源仍不确定：虽然有些人认为这些是肌肉起源的肿瘤，另一些人则假定为神经内分泌起源，但迄今为止积累的证据相互矛盾，因此这些肿瘤仍被视为起源不明的肿瘤。手术切除是主要的治疗方法。
