Macák J, Smyslová O, Krc I, Dusková M, Zapletal P
Ustav patologie Lékarské fakulty UP, Olomouc.
Cesk Patol. 1998 Jul;34(3):89-93.
Hodgkin's disease with a conspicuous presence of epithelioid-histiocytic elements was described as a particular subvariant of mixed type Hodgkin's disease. The authors presented four new cases. An additional increase of Langerhan's and interdigitating cells was observed in two cases, sarcoidosis-like granulomas with epithelioid and big multinucleated cells in the third. This female died and granulomas were found in several other organs. A prognostic relevance of this conspicuous reaction has not been clear for the time being. The mentioned patient deceased one year after the diagnosis had been settled, other three patients have been clinically well surviving 2-5 years.
霍奇金淋巴瘤伴有明显的上皮样组织细胞成分,被描述为混合型霍奇金淋巴瘤的一种特殊亚型。作者报告了4例新病例。其中2例观察到朗格汉斯细胞和指状突细胞进一步增多,第3例出现类似结节病的肉芽肿,伴有上皮样细胞和大的多核细胞。该女性患者死亡,在其他几个器官中发现了肉芽肿。目前尚不清楚这种明显反应的预后相关性。上述患者在确诊后1年死亡,其他3例患者临床情况良好,已存活2至5年。