Iyengar Krishnan R, Mutha Sucheeta
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605006, India.
Diagn Cytopathol. 2002 Mar;26(3):142-4. doi: 10.1002/dc.10080.
Diagnosis of Hodgkin's disease is made with more confidence than diagnosis of non-Hodgkin's lymphoma on cytology. This study was undertaken to describe the presence of granulomas and a new cytologic feature, discrete epithelioid cells (DECs), in smears from Hodgkin's disease. Fine-needle aspiration smears from 39 cases of biopsy-proven Hodgkin's disease, collected over a period of 43 months, were reviewed. Epithelioid granulomas were seen in 38.5% of the smears. DECs, which were noted in 70% of the cases, may be useful in raising the suspicion of Hodgkin's disease when other features are not evident; their presence should encourage the cytopathologist to obtain aspirations from other lymph nodes.
与非霍奇金淋巴瘤的细胞学诊断相比，霍奇金病的诊断更具确定性。本研究旨在描述霍奇金病涂片上肉芽肿的存在情况以及一种新的细胞学特征——离散上皮样细胞（DECs）。回顾了在43个月期间收集的39例经活检证实的霍奇金病患者的细针穿刺涂片。在38.5%的涂片上可见上皮样肉芽肿。在70%的病例中发现了离散上皮样细胞，当其他特征不明显时，它们可能有助于提高对霍奇金病的怀疑；它们的存在应促使细胞病理学家从其他淋巴结获取穿刺样本。
