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[听神经瘤患者半球小脑皮质结构变化中的神经营养不良成分]

[The neurodystrophic component of the structural changes in the hemispheric cerebellar cortex of patients with acoustic neurinomas].

作者信息

Shustova T I

出版信息

Vestn Otorinolaringol. 1998(4):33-5.

PMID:9752095
Abstract

Cerebellar specimens removed in surgical treatment of acoustic nerve neurinomas were studied morphologically in 16 patients. Histochemically, morphofunctional state of the vegetative adrenergic nervous fibers and endings of the vessels and connective tissue basis of the pia mater encephali in the region of the cerebellum indicates inhibited activity of the neuromediator contour of circulation and metabolism regulation in the brain. Light and electron microscopy in the cerebellar cortex detected disorders of circulation, nervous cell dystrophy, glyocytic proliferation. Correlation was found between activity of sympathetic component of the autonomic nervous system, severity of neurodystrophic changes in the cerebellar cortex and development of pathophysiological reactions arising intraoperatively and early after operation.

摘要

对16例接受听神经神经鞘瘤手术治疗时切除的小脑标本进行了形态学研究。组织化学研究表明,小脑区域脑软膜的植物性肾上腺素能神经纤维以及血管和结缔组织基质的形态功能状态显示出大脑中神经介质循环和代谢调节轮廓的活性受到抑制。在小脑皮质进行的光镜和电镜检查发现了循环障碍、神经细胞营养不良和神经胶质细胞增生。自主神经系统交感成分的活性、小脑皮质神经营养不良变化的严重程度与术中及术后早期出现的病理生理反应的发展之间存在相关性。

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