Doldi S B
Istituto di Chirurgia Generale ed Oncologia Chirurgica, Ospedale Policlinico, Milano, Italy.
Ann Chir. 1998;52(2):125-31.
The authors present their experience at the Centre for the surgical treatment of morbid obesity at Milano University where since 1974, 603 obese patients underwent surgery: 312 jejuno-ileal bypass (JIB), 70 bilio-intestinal bypass (BIB), 102 horizontal gastroplasties (HGP), 44 silastic ring vertical gastroplasties (SRVGP) and 75 adjustable silastic gastric banding (ASGB). Average follow-up for these procedures is 16, 6, 11, 4 years and 24 months respectively. Weight loss is satisfactory in all cases even though the percentages vary in the different procedures. The most serious complications (severe hepatic failure, oxalic interstitial nephritis, persisting malabsorption) occurred in patients submitted to JIB. The best clinical outcome with the lowest complications rate was obtained with BIB compared to other intestinal bypasses. The most frequent complication observed in patients submitted to gastroplasties was incoercible vomiting while the most severe complications were diffuse peritonitis, secondary to gastric perforation, and peripheric neuropathy. Our experience confirms that surgical treatment of morbid obesity refractory to medical therapy is today a safe and effective treatment. BIB has still a role in super-obese young patients (BMI over 50) refusing dietary restriction lifetime. The gastric procedures, especially laparoscopic ASGB, seem to be the best option. The excellent outcome of bariatric surgery can be obtained only in specialized centers where various specialists work together.
作者介绍了他们在米兰大学病态肥胖手术治疗中心的经验,自1974年以来,603例肥胖患者接受了手术:312例行空肠回肠旁路术(JIB),70例行胆肠旁路术(BIB),102例行水平胃成形术(HGP),44例行硅橡胶环垂直胃成形术(SRVGP),75例行可调节硅橡胶胃束带术(ASGB)。这些手术的平均随访时间分别为16年、6年、11年、4年和24个月。尽管不同手术的减重百分比有所不同,但所有病例的体重减轻情况均令人满意。最严重的并发症(严重肝衰竭、草酸间质肾炎、持续吸收不良)发生在接受JIB手术的患者中。与其他肠道旁路术相比,BIB手术获得了最佳的临床效果和最低的并发症发生率。接受胃成形术的患者中最常见的并发症是顽固性呕吐,而最严重的并发症是胃穿孔继发的弥漫性腹膜炎和周围神经病变。我们的经验证实,对于药物治疗无效的病态肥胖患者,手术治疗如今是一种安全有效的治疗方法。BIB手术在拒绝终身饮食限制的超级肥胖年轻患者(BMI超过50)中仍有作用。胃部手术,尤其是腹腔镜ASGB,似乎是最佳选择。只有在多学科专家共同协作的专业中心才能获得肥胖症手术的卓越疗效。