Volozhin A I, Shekhter A B, Karakov K G, Sukhanov Iu P, Gavril'chak A V, Popov V K, Antonov E N, Karrot M
Stomatologiia (Mosk). 1998;77(4):4-8.
The process of extraction of admixtures from acryl plastic widely used in dentistry by means of supercritical carbon dioxide (sc-CO2) was studied and effects of extraction conditions on biocompatibility and toxicity of resultant materials assessed, sc-CO2 effectively purified the specimens from toxic compounds (monomers and low-molecular oligomers, methylmethacrylate, dichloroethane) and notably improved the biocompatability of polymer implants. Tissue reaction to ethacryl and protacryl depends on the degree of implant polymerization and duration of extraction of toxic substances from polymer.
研究了利用超临界二氧化碳（sc-CO₂）从牙科广泛使用的丙烯酸塑料中提取外加剂的过程，并评估了提取条件对所得材料生物相容性和毒性的影响。sc-CO₂有效地从有毒化合物（单体和低分子低聚物、甲基丙烯酸甲酯、二氯乙烷）中净化了标本，并显著提高了聚合物植入物的生物相容性。组织对乙丙烯酸酯和原丙烯酸酯的反应取决于植入物的聚合程度以及从聚合物中提取有毒物质的持续时间。
