Noda Y, Uchinuno Y, Shirakawa H, Nagasue S, Nagano N, Ohe R, Narita M
Ryochiku Livestock Hygiene Service Center, Kurume, Fukuoka, Japan.
Vet Pathol. 1998 Sep;35(5):409-11. doi: 10.1177/030098589803500511.
A bovine fetus aborted at 187 days of gestation was serologically and immunohistopathologically examined. Serum and cerebrospinal fluid samples had high titers of virus-neutralizing antibody for Aino virus. A severe necrotizing encephalopathy was noted. Aino virus antigen was demonstrated in neuroglial cells within the brain lesion. The destruction of developing neuronal cells appeared to be a significant feature of the pathogenesis of lesions due to Aino virus infection in the central nervous system.
对一头在妊娠187天时流产的牛胎儿进行了血清学和免疫组织病理学检查。血清和脑脊液样本中抗爱诺病毒的病毒中和抗体滴度很高。发现有严重的坏死性脑病。在脑损伤部位的神经胶质细胞中检测到爱诺病毒抗原。发育中的神经元细胞的破坏似乎是中枢神经系统中爱诺病毒感染所致病变发病机制的一个显著特征。
