Schaub R G, Meyers K M, Sande R D, Hamilton G
Circ Res. 1976 Nov;39(5):736-43. doi: 10.1161/01.res.39.5.736.
We compared development of feline hindlimb collateral circulation after acute occlusion of the terminal aorta by ligation, thrombus formation, and formation of a "closed" aortic loop containing thromboplastin. Collateral circulation development was assessed by aortograms, scintillation scans, neurological signs following occlusion, measurement of hindlimb muscle blood flow, and forelimb and hindlimb temperature. In cats in which aortic occlusion was the result of ligation or thromboplastin in the aortic loop, paralysis was not evident. Aortograms and scintillation scans indicated hindlimb blood flow. Both muscle temperature and blood flow data indicated that the return of blood flow was rapid. The 5th lumbar artery appears to be the origin of the collateral vessels. The mid-zone component is a dorsal and ventral vertebral route and an epaxial muscle route. The reentry components are the 6th or 7th lumbar arteries. The collateral vessels arise from preexisting collateral vessels. Of those cats in which aortic occlusion was the result of a thrombus, all exhibited paralysis. Aortograms, scintillation scans, muscle temperature, and hindlimb blood flow data indicated reduced hindlimb blood flow. The results suggest that the thrombus has an inhibitory effect on the development of collateral circulation.
我们比较了通过结扎、血栓形成以及形成含凝血活酶的“闭合”主动脉环来急性闭塞终末主动脉后猫后肢侧支循环的发育情况。通过主动脉造影、闪烁扫描、闭塞后的神经体征、后肢肌肉血流测量以及前肢和后肢温度来评估侧支循环的发育。在主动脉闭塞是由结扎或主动脉环中的凝血活酶导致的猫中，未出现明显的麻痹。主动脉造影和闪烁扫描显示有后肢血流。肌肉温度和血流数据均表明血流恢复迅速。第五腰动脉似乎是侧支血管的起源。中区部分是一条背侧和腹侧的椎体路径以及一条轴上肌路径。再入部分是第六或第七腰动脉。侧支血管源自先前存在的侧支血管。在那些主动脉闭塞是由血栓导致的猫中，所有猫都出现了麻痹。主动脉造影、闪烁扫描、肌肉温度和后肢血流数据表明后肢血流减少。结果表明，血栓对侧支循环的发育具有抑制作用。
