Meining A, Kroher G, Stolte M
Dept. of Medicine II, Klinikum rechts der Isar, Technical University of Munich, Germany.
Scand J Gastroenterol. 1998 Aug;33(8):795-8. doi: 10.1080/00365529850171422.
Infection with either Helicobacter heilmannii or H. pylori causes gastritis in humans. Whereas the route of transmission of H. pylori appears to be human-human, it has been suggested that H. heilmannii is transmitted by animals.
Two hundred and two patients with histologically confirmed H. heilmannii gastritis and 600 randomly selected patients with H. pylori gastritis were sent a questionnaire, in which they were asked whether they had had or still have regular contact with dogs, cats, rodents, horses, birds, cattle, pigs, or wild animals.
The questionnaires of 177 patients with H. heilmannii and 485 with H. pylori infection were evaluated. In comparison with H. pylori, H. heilmanii infection was strongly associated with contact with dogs, cats, cattle, or pigs. Logistic regression analysis showed that contact with pigs, cats, and dogs leads to a significant risk of H. heilmannii infection (odds, 4.990, 1.710. and 1.462).
Pigs, cats, and dogs appear to be reservoirs in the transmission of H. heilmannii.
感染海尔曼幽门螺杆菌或幽门螺杆菌均会导致人类患胃炎。幽门螺杆菌的传播途径似乎是人际传播，而有人提出海尔曼幽门螺杆菌是通过动物传播的。
向202例经组织学确诊为海尔曼幽门螺杆菌胃炎的患者和600例随机选取的幽门螺杆菌胃炎患者发放问卷，询问他们是否曾经或仍与狗、猫、啮齿动物、马、鸟、牛、猪或野生动物有定期接触。
对177例海尔曼幽门螺杆菌感染患者和485例幽门螺杆菌感染患者的问卷进行了评估。与幽门螺杆菌相比，海尔曼幽门螺杆菌感染与接触狗、猫、牛或猪密切相关。逻辑回归分析表明，接触猪、猫和狗会导致感染海尔曼幽门螺杆菌的风险显著增加（比值分别为4.990、1.710和1.462）。
猪、猫和狗似乎是海尔曼幽门螺杆菌传播的宿主。
