Büyükaşik Y, Koşar A, Demiroğlu H, Altinok G, Ozcebe O I, Dündar S
Department of Internal Medicine, Hacettepe University Medical School, Ankara, Turkey.
J Clin Gastroenterol. 1998 Sep;27(2):146-8. doi: 10.1097/00004836-199809000-00009.
Acalculous acute cholecystitis (AAC) is a well-known complication in critically ill patients. However, there is no satisfactory data regarding this complication in leukemic patients. We reviewed the medical records of 426 patients with acute or chronic leukemia retrospectively to investigate the incidence, possible pathogenetic mechanisms, and clinical course of AAC in leukemia. Six cases of AAC were identified. The incidence was 1.65% (5/302) for acute leukemias. Three out of 6 patients underwent cholecystectomy, and two recovered completely. Percutaneous cholecystostomy was performed in another patient successfully. Careful histological examinations of the surgical specimens did not reveal any specific etiopathogenetic finding. However, clinical data suggested that infectious agents and visceral ischemia may contribute to the pathogenesis of AAC in leukemia.
无结石性急性胆囊炎（AAC）是危重症患者中一种众所周知的并发症。然而，关于白血病患者发生这种并发症的情况，目前尚无令人满意的数据。我们回顾性分析了426例急性或慢性白血病患者的病历，以研究白血病患者中AAC的发病率、可能的发病机制及临床病程。共确诊6例AAC。急性白血病患者的发病率为1.65%（5/302）。6例患者中有3例行胆囊切除术，2例完全康复。另1例患者成功接受了经皮胆囊造瘘术。对手术标本进行的仔细组织学检查未发现任何特异性的病因学发现。然而，临床资料提示，感染因素和内脏缺血可能在白血病患者AAC的发病机制中起作用。
